Study appraisal and synthesis Research Paper Example | Topics and Well Written Essays - 250 words

Study appraisal and synthesis - Research Paper ExampleThe study concept was very thorough using the prospective, randomized, open, blinded endpoint evaluation (PROBE) design. The sample size provides an adequate statistical power of 80%. Statistical depth psychology use Kaplan-Meier survival curves will take censored selective information into account, namely if a patient withdraws from the study and the variance of patient simvastatin doses. Logrank analysis and the Coxs regression model are conquer testing methods widely used in survival analysis to establish the efficacy of a new treatment (aspirin and statins) compared to a control treatment (statins) in succession to event measurements. Use of the Mantel-Haenszel procedure to test subgroups will be effective providing subgroup sample sizes are vainglorious enough to obtain stable estimates. Interim analysis after 50% of events had occurred leaves scope for adjustments to the study.The study linguistic context was relevant b ecause the sample consisted of patients who had no history of cardiovascular disease, who were type 1 and type 2 diabetic and who were already prescribed or candidates for the use of statins.Participants were appropriately defined for the study and selected based on appropriate criteria. A clear follow up plan is defined to maintain patient health with changes to simvastatin control treatment doses allowed based on clinical judgment If LDL cholesterol levels were 100 mg/dL (2.59 mmol/L). Losses are expected